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Guide to Silicone Hoses (FDA & USP Class VI) | Glory Engineering
Braided Silicone Hose High-Purity Pharmaceutical Silicone Hose Silicone Hose with Sanitary Tri-Clamp Fittings

High-Purity Silicone Hoses (FDA & USP Class VI)

Silicone Hoses are the premium choice for applications in the **Pharmaceutical, Food & Beverage, and Medical** industries where purity, high-temperature resistance, and flexibility are paramount. Unlike rubber or PVC, silicone is a high-purity polymer known for being non-toxic, non-leaching, and having zero taste or odor.

This guide from Glory Engineering Supplies serves as a complete technical reference. It is designed for engineers, quality assurance, and bioprocess specialists to understand the critical **platinum-cured** material, **FDA & USP Class VI** compliance, and hygienic assemblies required for the most sensitive processes.

Why Choose Glory Silicone Hoses?

USP Class VI & FDA Certified

Our hoses meet the most stringent biocompatibility and safety standards, making them ideal for pharmaceutical and food-grade use.

Platinum-Cured Standard

We supply platinum-cured hoses, which offer the highest purity, lowest extractables, and no byproducts (unlike peroxide-cured), ensuring product integrity.

High-Temperature Performance

Silicone is autoclavable and excellent for SIP (Sterilization-in-Place) and transferring hot products where other materials would fail.

Hygienic Sanitary Assemblies

We provide professional, crevice-free sanitary crimping of 316L SS Tri-Clamp fittings, ensuring a fully cleanable, hygienic system.

Understanding Silicone Hose Types

Silicone hoses are reinforced based on the application's pressure or vacuum requirements.

Hose Type Reinforcement Key Characteristics & Common Use
Unreinforced Silicone Tube None (Translucent Tube)
  • Low pressure, high flexibility.
  • Use for: Peristaltic pumps, sight glass, non-pressurized product transfer, lab use.
Braided Silicone Hose Polyester or Aramid (Kevlar) textile braid.
  • The "standard" for pressure.
  • Use for: Medium-pressure product transfer, CIP/SIP lines, and general processing. Remains very flexible.
Wire-Reinforced Silicone Hose Stainless steel or plastic wire helix.
  • For Suction & Discharge (S&D).
  • Use for: Vacuum applications, suction lines, and high-durability floor use. The helix prevents collapse under suction.

Technical Data: Typical Working Pressure (PSI / Bar)

This chart shows the typical Maximum Working Pressure (MWP) for silicone hoses at 20°C (70°F). Silicone is a soft material; pressure ratings are generally lower than for rubber hoses.

Hose Size (ID) Unreinforced Tube Braided Hose Wire-Reinforced (S&D)
1/2" ~40 PSI2.8 Bar 250 PSI17.2 Bar 150 PSI10.3 BarFull Vacuum
3/4" ~30 PSI2.1 Bar 200 PSI13.8 Bar 125 PSI8.6 BarFull Vacuum
1" ~20 PSI1.4 Bar 150 PSI10.3 Bar 100 PSI6.9 BarFull Vacuum
1-1/2" N/A 125 PSI8.6 Bar 80 PSI5.5 BarFull Vacuum
2" N/A 100 PSI6.9 Bar 75 PSI5.2 BarFull Vacuum
3" N/A 75 PSI5.2 Bar 60 PSI4.1 BarFull Vacuum
4" N/A 50 PSI3.4 Bar 50 PSI3.4 BarFull Vacuum

Hygienic Sanitary Fittings

For pharmaceutical and food use, all fittings must be "sanitary" and crevice-free. The connection is permanently crimped to the hose.

Sanitary Tri-Clamp (TC) Fitting

Tri-Clamp (TC)

The #1 industry standard for Pharma & Food. A quick-disconnect fitting that joins two ends with a gasket and a clamp. Easy to clean and inspect.

Hygienic Sanitary Crimp Ferrule

Sanitary Crimp

The ONLY way to attach fittings. A stainless steel ferrule is crimped over the hose, creating a smooth, permanent, crevice-free transition from hose to fitting.

DIN 11851 Sanitary Fitting

DIN / SMS

Other common threaded sanitary union standards, popular in Europe and globally. We can provide assemblies with these ends.

Bevel Seat Sanitary Fitting

316L Stainless Steel

All our sanitary fittings are made from 316L Stainless Steel, which offers superior corrosion resistance and purity compared to 304 SS.

Silicone Hose Installation & Care

Proper handling is critical to protect the soft silicone material and maintain system purity.

DO: Clean & Sterilize (CIP/SIP)

Solution: Silicone is excellent for **Autoclaving** and **CIP/SIP**. Hoses MUST be thoroughly cleaned and sterilized before and after every use to prevent contamination.

DON'T: Exceed Bend Radius

Problem: Bending the hose too sharply creates a kink, which restricts flow, damages the reinforcement, and becomes a weak point that can fail.

DON'T: Over-Tighten Clamps

Problem: Silicone is a soft material. Over-tightening Tri-Clamps or mounting clamps can cut or damage the hose cover, leading to failure. Tighten only until a seal is formed.

DON'T: Drag or Twist

Problem: Twisting the hose during install will damage the braid. Dragging the hose on rough floors will damage the soft silicone cover. Handle with care.

Common Pharmaceutical & Food Applications

  • Pharmaceutical: Ultra-pure water (WFI), product transfer, bioreactor and fermenter lines, cell culture, filling and dispensing.
  • Food & Beverage: High-temperature product transfer (hot syrups, sauces, jams), cosmetic production, dairy, and brewery "hot side" lines.
  • General: Peristaltic pump tubing (unreinforced), high-temperature air/water lines, and any process requiring high purity and flexibility.

Frequently Asked Questions (FAQ)

What is "Platinum-Cured" vs. "Peroxide-Cured"?

This is the curing (vulcanizing) process. Peroxide-cured is cheaper but can leave byproducts (like dicumyl peroxide) which may leach into the product. Platinum-cured is a cleaner, addition-cure process. It leaves no byproducts, has the lowest extractables, and is the gold standard for pharmaceutical and high-purity food applications.

What is "USP Class VI"?

The U.S. Pharmacopeia (USP) Class VI is a stringent biocompatibility standard. It involves rigorous testing to ensure the material is non-toxic and non-reactive when it comes into contact with human tissue or fluids. It is a mandatory requirement for most medical and pharmaceutical-grade materials.

What is the difference between Silicone and EPDM Rubber?

Both are used in food processing, but for different jobs. Silicone is superior for high temperatures and purity (non-leaching) but is softer and has lower pressure/abrasion resistance. EPDM Rubber (like on a brewery hose) is much more durable, has a higher pressure rating, and better abrasion resistance, but a lower temperature limit than silicone.

Can silicone hose be used for a vacuum?

Only if it is wire-reinforced. Standard unreinforced or braided silicone hoses are "soft-walled" and will collapse under a vacuum. A **wire-reinforced** hose has a steel or plastic helix specifically designed to prevent collapse, making it suitable for suction.

Get Your High-Purity Hose Assembly

From WFI transfer lines to hot-fill food processing, our team provides certified, high-purity silicone hose assemblies. Contact us to discuss your specific pharmaceutical or food-grade application today.

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